Endocrine Abstracts

Introduction: An HbA1c target level of 48 mmol/mol or lower in children with type 1 diabetes is recommended by the National Institute for Health and Care Excellence. Only 7.1% (national average 7.2%) of children in our unit achieved this target. In response, during a multidisciplinary diabetes away day, we explored innovative approaches to timely and efficient identification and intervention in patients with high HbA1c levels. The National Paediatric Diabetes Audit web portal,...

Obesity, as a chronic nutritional disorder, is a high-risk factor for type 2 diabetes, fatty liver and other metabolic diseases. Multiple lncRNAs have been confirmed concerning adipocyte differentiation and thus affect obesity, such as ADINR, Paral1, etc. Previously, we identified a lncRNA named ENST0000052114 (abbreviated to lncRNA52114), highly expressed in human mature adipocytes by differential lncRNA expression profile. Here, we explored the role and mechanism of lncRNA52...